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Valproate, a Mood Stabilizer, Induces WFS1 Expression and Modulates Its Interaction with ER Stress Protein GRP94

BACKGROUND: Valproate is a standard treatment for bipolar disorder and a first-line mood stabilizer. The molecular mechanisms underlying its actions in bipolar disorder are unclear. It has been suggested that the action of valproate is linked to changes in gene expression and induction of endoplasmi...

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Detalles Bibliográficos
Autores principales: Kakiuchi, Chihiro, Ishigaki, Shinsuke, Oslowski, Christine M., Fonseca, Sonya G., Kato, Tadafumi, Urano, Fumihiko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607540/
https://www.ncbi.nlm.nih.gov/pubmed/19125190
http://dx.doi.org/10.1371/journal.pone.0004134