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Valproate, a Mood Stabilizer, Induces WFS1 Expression and Modulates Its Interaction with ER Stress Protein GRP94
BACKGROUND: Valproate is a standard treatment for bipolar disorder and a first-line mood stabilizer. The molecular mechanisms underlying its actions in bipolar disorder are unclear. It has been suggested that the action of valproate is linked to changes in gene expression and induction of endoplasmi...
Autores principales: | Kakiuchi, Chihiro, Ishigaki, Shinsuke, Oslowski, Christine M., Fonseca, Sonya G., Kato, Tadafumi, Urano, Fumihiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607540/ https://www.ncbi.nlm.nih.gov/pubmed/19125190 http://dx.doi.org/10.1371/journal.pone.0004134 |
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