Cargando…

Peptides Derived from HIV-1 Integrase that Bind Rev Stimulate Viral Genome Integration

BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) integrase protein (IN), catalyzes the integration of viral DNA into the host cell genome. IN catalyzes the first step of the integration process, namely the 3′-end processing in which IN removes a pGT dinucleotide from the 3′ end of each vi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Levin, Aviad, Hayouka, Zvi, Helfer, Markus, Brack-Werner, Ruth, Friedler, Assaf, Loyter, Abraham
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607543/ https://www.ncbi.nlm.nih.gov/pubmed/19127291 http://dx.doi.org/10.1371/journal.pone.0004155

Ejemplares similares

Peptides derived from the HIV-1 integrase promote HIV-1 infection and multi-integration of viral cDNA in LEDGF/p75-knockdown cells
por: Levin, Aviad, et al.
Publicado: (2010)

Specific eradication of HIV-1 from infected cultured cells
por: Levin, Aviad, et al.
Publicado: (2010)

Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal
por: Levin, Aviad, et al.
Publicado: (2009)

Identification of a novel Rev-interacting cellular protein
por: Kramer-Hämmerle, Susanne, et al.
Publicado: (2005)

Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors
por: Pabis, Marta, et al.
Publicado: (2019)

Potent in vitro antiviral activity of Cistus incanus extract against HIV and Filoviruses targets viral envelope proteins
por: Rebensburg, Stephanie, et al.
Publicado: (2016)

Integrase-derived peptides together with CD24-targeted lentiviral particles inhibit the growth of CD24 expressing cancer cells
por: Shapira, Shiran, et al.
Publicado: (2021)

Heterogenous nuclear ribonucleoprotein Q increases protein expression from HIV-1 Rev-dependent transcripts
por: Vincendeau, Michelle, et al.
Publicado: (2013)

Antimicrobial Peptide Combination Can Hinder Resistance Evolution
por: Maron, Bar, et al.
Publicado: (2022)

PRMT6 diminishes HIV-1 Rev binding to and export of viral RNA
por: Invernizzi, Cédric F, et al.
Publicado: (2006)

Mapping the Binding Interface between an HIV-1 Inhibiting Intrabody and the Viral Protein Rev
por: Vercruysse, Thomas, et al.
Publicado: (2013)

Deletion of the GI-2 integrase and the wbkA flanking transposase improves the stability of Brucella melitensis Rev 1 vaccine
por: Mancilla, Marcos, et al.
Publicado: (2013)

Pre-organized structure of viral DNA at the binding-processing site of HIV-1 integrase
por: Renisio, Jean-Guillaume, et al.
Publicado: (2005)

Impedimetric Bacterial Detection Using Random Antimicrobial Peptide Mixtures
por: Stern Bauer, Tal, et al.
Publicado: (2023)

HIV-1 integrase SUMOylation and viral replication
por: Zamborlini, Alessia, et al.
Publicado: (2011)

Structural and Functional Insights into Foamy Viral Integrase
por: Hossain, Md. Alamgir, et al.
Publicado: (2013)

Random peptide mixtures entrapped within a copper-cuprite matrix: new antimicrobial agent against methicillin-resistant Staphylococcus aureus
por: Bauer, Tal Stern, et al.
Publicado: (2019)

Elucidating the Hot Spot Residues of Quorum Sensing Peptidic Autoinducer PapR by Multiple Amino Acid Replacements
por: Yehuda, Avishag, et al.
Publicado: (2019)

A Paper-Based Near-Infrared Optical Biosensor for Quantitative Detection of Protease Activity Using Peptide-Encapsulated SWCNTs
por: Shumeiko, Vlad, et al.
Publicado: (2020)

HIV-1 Integrase-Targeted Short Peptides Derived from a Viral Protein R Sequence
por: Zhao, Xue Zhi, et al.
Publicado: (2018)

Accelerated Multiphosphorylated Peptide Synthesis
por: Grunhaus, Dana, et al.
Publicado: (2022)

Aqueous Extracts of the Marine Brown Alga Lobophora variegata Inhibit HIV-1 Infection at the Level of Virus Entry into Cells
por: Kremb, Stephan, et al.
Publicado: (2014)

Cardiolipin is an Optimal Phospholipid for the Assembly, Stability, and Proper Functionality of the Dimeric Form of NhaA Na(+)/H(+) Antiporter
por: Rimon, Abraham, et al.
Publicado: (2019)

An Unusual Helix Turn Helix Motif in the Catalytic Core of HIV-1 Integrase Binds Viral DNA and LEDGF
por: Merad, Hayate, et al.
Publicado: (2009)

Foamy Virus Integrase in Development of Viral Vector for Gene Therapy
por: Kim, Jinsun, et al.
Publicado: (2020)

Random peptide mixtures as new crop protection agents
por: Topman, Shiri, et al.
Publicado: (2018)

The Root Extract of the Medicinal Plant Pelargonium sidoides Is a Potent HIV-1 Attachment Inhibitor
por: Helfer, Markus, et al.
Publicado: (2014)

Regulation of Circadian Behavior and Metabolism by Rev-erbα and Rev-erbβ
por: Cho, Han, et al.
Publicado: (2012)

A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope
por: Luteijn, Rutger D., et al.
Publicado: (2020)

HIV-1 resists MxB inhibition of viral Rev protein
por: Wang, Zhen, et al.
Publicado: (2020)

Differential effects of zinc binding on structured and disordered regions in the multidomain STIL protein
por: Amartely, Hadar, et al.
Publicado: (2016)

Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase
por: Mauro, Eric, et al.
Publicado: (2019)

Specificity of RSG-1.2 Peptide Binding to RRE-IIB RNA Element of HIV-1 over Rev Peptide Is Mainly Enthalpic in Origin
por: Kumar, Santosh, et al.
Publicado: (2011)

A Possible Role for the Asymmetric C-Terminal Domain Dimer of Rous Sarcoma Virus Integrase in Viral DNA Binding
por: Shi, Ke, et al.
Publicado: (2013)

Integrase and integration: biochemical activities of HIV-1 integrase
por: Delelis, Olivier, et al.
Publicado: (2008)

Limited nucleotide changes of HIV-1 subtype B Rev response element in China affect overall Rev-RRE activity and viral replication
por: Shi, Yuting, et al.
Publicado: (2022)

RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev–Rev response element complex
por: Jayaraman, Bhargavi, et al.
Publicado: (2014)

Allosteric modulation of protein oligomerization: an emerging approach to drug design
por: Gabizon, Ronen, et al.
Publicado: (2014)

REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ
por: Tomida, Junya, et al.
Publicado: (2015)

Alkaloids from the Sponge Stylissa carteri Present Prospective Scaffolds for the Inhibition of Human Immunodeficiency Virus 1 (HIV-1)
por: O’Rourke, Aubrie, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_r4sc1o78cfmkv47uq87b4uobra