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Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin

BACKGROUND: Bone resorption displays marked diurnal variation. Reversible inhibition of bone resorption may result in best possible efficacy when bone resorption peaks. The aim of the study was to assess the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of 0.8 mg of oral salmon calcitonin (...

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Detalles Bibliográficos
Autores principales:	Karsdal, MA, Byrjalsen, I, Riis, BJ, Christiansen, C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2611964/ https://www.ncbi.nlm.nih.gov/pubmed/19055791 http://dx.doi.org/10.1186/1472-6904-8-12

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