Deletion Hotspots in AMACR Promoter CpG Island Are cis-Regulatory Elements Controlling the Gene Expression in the Colon

Alpha-methylacyl-coenzyme A racemase (AMACR) regulates peroxisomal β-oxidation of phytol-derived, branched-chain fatty acids from red meat and dairy products — suspected risk factors for colon carcinoma (CCa). AMACR was first found overexpressed in prostate cancer but not in benign glands and is now...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang, Leav, Irwin, Revelo, Monica P., Deka, Ranjan, Medvedovic, Mario, Jiang, Zhong, Ho, Shuk-Mei
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613032/
https://www.ncbi.nlm.nih.gov/pubmed/19148275
http://dx.doi.org/10.1371/journal.pgen.1000334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613032/
https://www.ncbi.nlm.nih.gov/pubmed/19148275
http://dx.doi.org/10.1371/journal.pgen.1000334

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