In vitro allergen challenge of peripheral blood induces differential gene expression in mononuclear cells of asthmatic patients: inhibition of cytosolic phospholipase A(2α) overcomes the asthma-associated response

BACKGROUND: Existing treatments for asthma are not effective in all patients and disease exacerbations are common, highlighting the need for increased understanding of disease mechanisms and novel treatment strategies. The leukotriene pathway including the enzyme responsible for arachidonic acid rel...

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Detalles Bibliográficos
Autores principales: Whalen, K A, Legault, H, Hang, C, Hill, A, Kasaian, M, Donaldson, D, Bensch, G W, Bensch, G, Baker, J, Reddy, P S, Wood, N, Ramarao, M K, Ellis, D K, Csimma, C, McKee, C, Clark, J D, Ryan, J, Dorner, A J, O'Toole, M
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Original Paper: Asthma and Rhinitis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613256/
https://www.ncbi.nlm.nih.gov/pubmed/18665843
http://dx.doi.org/10.1111/j.1365-2222.2008.03059.x

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