Cargando…

PEG Minocycline-Liposomes Ameliorate CNS Autoimmune Disease

BACKGROUND: Minocycline is an oral tetracycline derivative with good bioavailability in the central nervous system (CNS). Minocycline, a potent inhibitor of matrix metalloproteinase (MMP)-9, attenuates disease activity in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Wei, Metselaar, Josbert, Ben, Li-Hong, Cravens, Petra D., Singh, Mahendra P., Frohman, Elliot M., Eagar, Todd N., Racke, Michael K., Kieseier, Bernd C., Stüve, Olaf
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613526/ https://www.ncbi.nlm.nih.gov/pubmed/19127301 http://dx.doi.org/10.1371/journal.pone.0004151

Ejemplares similares

Rituximab Therapy Reduces Organ-Specific T Cell Responses and Ameliorates Experimental Autoimmune Encephalomyelitis
por: Monson, Nancy L., et al.
Publicado: (2011)

The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis
por: Cravens, Petra D, et al.
Publicado: (2013)

TLR3 agonism re‐establishes CNS immune competence during α4‐integrin deficiency
por: Hussain, Rehana Z., et al.
Publicado: (2018)

CD11c(+)CD88(+)CD317(+) myeloid cells are critical mediators of persistent CNS autoimmunity
por: Manouchehri, Navid, et al.
Publicado: (2021)

Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling
por: Hu, Wei, et al.
Publicado: (2010)

A STAT3 inhibitor ameliorates CNS autoimmunity by restoring Teff:Treg balance
por: Aqel, Saba I., et al.
Publicado: (2021)

Quinpramine Ameliorates Rat Experimental Autoimmune Neuritis and Redistributes MHC Class II Molecules
por: Meyer zu Hörste, Gerd, et al.
Publicado: (2011)

Lymph node-derived donor encephalitogenic CD4(+ )T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet
por: Cravens, Petra D, et al.
Publicado: (2011)

Reactivation of Human Herpesvirus-6 in Natalizumab Treated Multiple Sclerosis Patients
por: Yao, Karen, et al.
Publicado: (2008)

Pain in Multiple Sclerosis: Understanding Pathophysiology, Diagnosis, and Management Through Clinical Vignettes
por: Racke, Michael K., et al.
Publicado: (2022)

Distinctive transcriptomic and epigenomic signatures of bone marrow-derived myeloid cells and microglia in CNS autoimmunity
por: Manouchehri, Navid, et al.
Publicado: (2023)

Recent Advances in Liposomal-Based Anti-Inflammatory Therapy
por: van Alem, Carla M. A., et al.
Publicado: (2021)

IL-12/IL-23p40 Is Highly Expressed in Secondary Lymphoid Organs and the CNS during All Stages of EAE, but Its Deletion Does Not Affect Disease Perpetuation
por: Cravens, Petra D., et al.
Publicado: (2016)

α4-integrin deficiency in B cells does not affect disease in a T-cell–mediated EAE disease model
por: Hussain, Rehana Z., et al.
Publicado: (2019)

B cell-based therapies in CNS autoimmunity: differentiating CD19 and CD20 as therapeutic targets
por: Forsthuber, Thomas G., et al.
Publicado: (2018)

CNS Intravascular Lymphoma: A Case Report
por: Awad, Amer, et al.
Publicado: (2011)

IL-3 Is a Marker of Encephalitogenic T Cells, but Not Essential for CNS Autoimmunity
por: Lee, Priscilla W., et al.
Publicado: (2018)

Heat exposure and bicycling trigger recurrent aseptic meningitis: a case report
por: Stuve, Olaf, et al.
Publicado: (2014)

Development and characterization of liposomal formulation of bortezomib
por: Deshantri, Anil K., et al.
Publicado: (2019)

Docosahexaenoic acid liposomes for targeting chronic inflammatory diseases and cancer: an in vitro assessment
por: Alaarg, Amr, et al.
Publicado: (2016)

Presenilin1 regulates Th1 and Th17 effector responses but is not required for experimental autoimmune encephalomyelitis
por: Cummings, Matthew, et al.
Publicado: (2018)

Identification of targets and new developments in the treatment of multiple sclerosis – focus on cladribine
por: Warnke, Clemens, et al.
Publicado: (2010)

Evaluation of subconjunctival liposomal steroids for the treatment of experimental uveitis
por: Wong, Chee Wai, et al.
Publicado: (2018)

Neuron-Specific Vitamin D Signaling Attenuates Microglia Activation and CNS Autoimmunity
por: Lee, Priscilla W., et al.
Publicado: (2020)

Critical appraisal of the role of fingolimod in the treatment of multiple sclerosis
por: Warnke, Clemens, et al.
Publicado: (2011)

Rapid Development of Autoimmune Hepatitis Secondary to Minocycline
por: Rafa, Omar, et al.
Publicado: (2022)

Review of teriflunomide and its potential in the treatment of multiple sclerosis
por: Warnke, Clemens, et al.
Publicado: (2009)

Local delivery of minocycline-loaded PEG-PLA nanoparticles for the enhanced treatment of periodontitis in dogs
por: Yao, Wenxin, et al.
Publicado: (2014)

Scale-Up of the Manufacturing Process To Produce Docetaxel-Loaded mPEG-b-p(HPMA-Bz) Block Copolymer Micelles for Pharmaceutical Applications
por: Bresseleers, Jaleesa, et al.
Publicado: (2019)

The Minocycline Ameliorated the Synaptic Plasticity Impairment in Vascular Dementia
por: Sharifi, Mohammad Davood, et al.
Publicado: (2021)

Peg-Grafted Liposomes for L-Asparaginase Encapsulation
por: de Souza Guimarães, Marina, et al.
Publicado: (2022)

Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS
por: Li, Zhilin, et al.
Publicado: (2020)

Aryl Hydrocarbon Receptor Activation in Astrocytes by Laquinimod Ameliorates Autoimmune Inflammation in the CNS
por: Rothhammer, Veit, et al.
Publicado: (2021)

Challenges in nanomedicine clinical translation
por: Metselaar, Josbert M., et al.
Publicado: (2020)

Erythropoietin Ameliorates Rat Experimental Autoimmune Neuritis by Inducing Transforming Growth Factor-Beta in Macrophages
por: Mausberg, Anne K., et al.
Publicado: (2011)

A phase I first-in-man study to investigate the pharmacokinetics and safety of liposomal dexamethasone in patients with progressive multiple myeloma
por: Metselaar, Josbert, et al.
Publicado: (2023)

Effect of PEG Pairing on the Efficiency of Cancer-Targeting Liposomes
por: Saw, Phei Er, et al.
Publicado: (2015)

Effect of Formulation and Processing Parameters on the Size of mPEG-b-p(HPMA-Bz) Polymeric Micelles
por: Bagheri, Mahsa, et al.
Publicado: (2018)

Dietary conjugated linoleic acid links reduced intestinal inflammation to amelioration of CNS autoimmunity
por: Fleck, Ann-Katrin, et al.
Publicado: (2021)

Quercetin Liposomal Nanoformulation for Ischemia and Reperfusion Injury Treatment
por: Ferreira-Silva, Margarida, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lj1ihgmvefre34k5ui0bcr2afv