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Granular Assembly of α-Synuclein Leading to the Accelerated Amyloid Fibril Formation with Shear Stress
α-Synuclein participates in the Lewy body formation of Parkinson's disease. Elucidation of the underlying molecular mechanism of the amyloid fibril formation is crucial not only to develop a controlling strategy toward the disease, but also to apply the protein fibrils for future biotechnology....
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613562/ https://www.ncbi.nlm.nih.gov/pubmed/19137068 http://dx.doi.org/10.1371/journal.pone.0004177 |