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Regulation of Chemerin Bioactivity by Plasma Carboxypeptidase N, Carboxypeptidase B (Activated Thrombin-activable Fibrinolysis Inhibitor), and Platelets
Chemerin is a potent chemoattractant for cells expressing the serpentine receptor CMKLR1 (chemokine-like receptor 1), such as plasmacytoid dendritic cells and tissue macrophages. The bioactivity of chemerin is post-translationally regulated; the attractant circulates in blood in a relatively inactiv...
Autores principales: | Du, Xiao-Yan, Zabel, Brian A., Myles, Timothy, Allen, Samantha J., Handel, Tracy M., Lee, Peter P., Butcher, Eugene C., Leung, Lawrence L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613638/ https://www.ncbi.nlm.nih.gov/pubmed/19010784 http://dx.doi.org/10.1074/jbc.M805000200 |
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