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Expression of BLIMP1/PRMT5 and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors

BACKGROUND: Most testicular germ cell tumors arise from intratubular germ cell neoplasia unclassified (IGCNU, also referred to as carcinoma in situ), which is thought to originate from a transformed primordial germ cell (PGC)/gonocyte, the fetal germ cell. Analyses of the molecular profile of IGCNU...

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Detalles Bibliográficos
Autores principales:	Eckert, Dawid, Biermann, Katharina, Nettersheim, Daniel, Gillis, Ad JM, Steger, Klaus, Jäck, Hans-Martin, Müller, Annette M, Looijenga, Leendert HJ, Schorle, Hubert
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613889/ https://www.ncbi.nlm.nih.gov/pubmed/18992153 http://dx.doi.org/10.1186/1471-213X-8-106

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