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Mouse Genome-Wide Association Mapping Needs Linkage Analysis to Avoid False-Positive Loci
We carried out genome-wide association (GWA) studies in inbred mouse strains characterized for their lung tumor susceptibility phenotypes (spontaneous or urethane-induced) with panels of 12,959 (13K) or 138,793 (140K) single-nucleotide polymorphisms (SNPs). Above the statistical thresholds, we detec...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614123/ https://www.ncbi.nlm.nih.gov/pubmed/19132132 http://dx.doi.org/10.1371/journal.pgen.1000331 |