Cargando…

Down-regulation of PPARgamma1 suppresses cell growth and induces apoptosis in MCF-7 breast cancer cells

BACKGROUND: Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of the nuclear hormone receptor superfamily and is highly expressed in many human tumors including breast cancer. PPARγ has been identified as a potential target for breast cancer therapy based on the fact that its acti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zaytseva, Yekaterina Y, Wang, Xin, Southard, R Chase, Wallis, Natalie K, Kilgore, Michael W
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614423/ https://www.ncbi.nlm.nih.gov/pubmed/19061500 http://dx.doi.org/10.1186/1476-4598-7-90

Ejemplares similares

Perfluorooctanesulfonate Mediates Renal Tubular Cell Apoptosis through PPARgamma Inactivation
por: Wen, Li-Li, et al.
Publicado: (2016)

PPARgamma Deficiency Counteracts Thymic Senescence
por: Ernszt, David, et al.
Publicado: (2017)

Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats
por: Yang, Baichun, et al.
Publicado: (2004)

Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer Cells
por: Ranganathan, Santhalakshmi, et al.
Publicado: (2015)

PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice
por: Shen, B, et al.
Publicado: (2012)

Berberine suppresses migration of MCF-7 breast cancer cells through down-regulation of chemokine receptors
por: Ahmadiankia, Naghmeh, et al.
Publicado: (2016)

TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma
por: Keuper, M, et al.
Publicado: (2013)

PPARgamma in Metabolism, Immunity, and Cancer: Unified and Diverse Mechanisms of Action
por: Hernandez-Quiles, Miguel, et al.
Publicado: (2021)

Initiation of apoptosis by photodynamic therapy on MCF7 cells
por: Kolacaronova, Hana, et al.
Publicado: (2001)

Proteins from Lignosus tigris with selective apoptotic cytotoxicity towards MCF7 cell line and suppresses MCF7-xenograft tumor growth
por: Kong, Boon Hong, et al.
Publicado: (2020)

PPARgamma-Dependent Control of Renin Expression: Molecular Mechanisms and Pathophysiological Relevance
por: Todorov, Vladimir T.
Publicado: (2013)

Growth Inhibition and Apoptosis Induction of Salvia chloroleuca on MCF-7 Breast Cancer Cell Line
por: Tayarani-Najaran, Zahra, et al.
Publicado: (2013)

MicroRNA-769-3p Down-regulates NDRG1 and Enhances Apoptosis in MCF-7 Cells During Reoxygenation
por: Luo, En-Ching, et al.
Publicado: (2014)

Identification of Novel Artemisinin Hybrids Induce Apoptosis and Ferroptosis in MCF-7 Cells
por: Zhong, Ye, et al.
Publicado: (2022)

Inhibition of Abelson Tyrosine-Protein Kinase 2 Suppresses the Development of Alcohol-Associated Liver Disease by Decreasing PPARgamma Expression
por: Malnassy, Greg, et al.
Publicado: (2023)

PPARgamma-2 and ADRB3 polymorphisms in connective tissue diseases and lipid disorders
por: Grygiel-Górniak, Bogna, et al.
Publicado: (2018)

PPARgamma: A Potential Intrinsic and Extrinsic Molecular Target for Breast Cancer Therapy
por: Augimeri, Giuseppina, et al.
Publicado: (2021)

Specific Thiazolidinediones Inhibit Ovarian Cancer Cell Line Proliferation and Cause Cell Cycle Arrest in a PPARγ Independent Manner
por: Al-Alem, Linah, et al.
Publicado: (2011)

Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM
por: Cheng, Xia, et al.
Publicado: (2019)

Recombinant adenoviruses expressing apoptin suppress the growth of MCF-7 breast cancer cells and affect cell autophagy
por: Chen, Shuang, et al.
Publicado: (2019)

Effects of 8-hydroxyquinoline-coated graphene oxide on cell death and apoptosis in MCF-7 and MCF-10 breast cell lines
por: Kheiltash, Firoozeh, et al.
Publicado: (2020)

Embelin-induced MCF-7 breast cancer cell apoptosis and blockade of MCF-7 cells in the G2/M phase via the mitochondrial pathway
por: LI, YANG, et al.
Publicado: (2013)

Dioscin strengthens the efficiency of adriamycin in MCF-7 and MCF-7/ADR cells through autophagy induction: More than just down-regulation of MDR1
por: Wang, Changyuan, et al.
Publicado: (2016)

Inhibition of Irvingia gabonensis seed extract (OB131) on adipogenesis as mediated via down regulation of the PPARgamma and Leptin genes and up-regulation of the adiponectin gene
por: Oben, Julius E, et al.
Publicado: (2008)

Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis
por: Alshatwi, Ali A
Publicado: (2010)

Cyperotundone combined with adriamycin induces apoptosis in MCF-7 and MCF-7/ADR cancer cells by ROS generation and NRF2/ARE signaling pathway
por: Shao, Wenna, et al.
Publicado: (2023)

Effect of HMGN2 on proliferation and apoptosis of MCF-7 breast cancer cells
por: Fan, Bo, et al.
Publicado: (2019)

Induction of Apoptosis and Cytotoxicity by Raphasatin in Human Breast Adenocarcinoma MCF-7 Cells
por: Ibrahim, Muhammad Din, et al.
Publicado: (2018)

The Synergistic Effects of Celastrol in combination with Tamoxifen on Apoptosis and Autophagy in MCF-7 Cells
por: Wang, Lijun, et al.
Publicado: (2021)

The Synergistic Combination of Cisplatin and Piperine Induces Apoptosis in MCF-7 Cell Line
por: Fattah, Abolfazl, et al.
Publicado: (2021)

EGFR Suppression Inhibits the Sphere Formation of MCF7 Cells Overexpressing EGFR
por: Novak, D. D., et al.
Publicado: (2023)

Lipid Metabolism as a Targetable Metabolic Vulnerability in Colorectal Cancer
por: Zaytseva, Yekaterina
Publicado: (2021)

Bitter melon extract suppresses metastatic breast cancer cells (MCF-7 cells) growth possibly by hindering glucose uptake
por: Kakuturu, Abhinav, et al.
Publicado: (2023)

Prostate apoptosis response-4 is involved in the apoptosis response to docetaxel in MCF-7 breast cancer cells
por: PEREIRA, MICHELLY C., et al.
Publicado: (2013)

Anti-inflammatory properties of a dual PPARgamma/alpha agonist muraglitazar in in vitro and in vivo models
por: Paukkeri, Erja-Leena, et al.
Publicado: (2013)

Stimulated Expression of CXCL12 in Adrenocortical Carcinoma by the PPARgamma Ligand Rosiglitazone Impairs Cancer Progression
por: Cantini, Giulia, et al.
Publicado: (2021)

Magnetic nanoparticles sensitize MCF-7 breast cancer cells to doxorubicin-induced apoptosis
por: Aljarrah, Khaled, et al.
Publicado: (2012)

The Signaling Cascades of Ginkgolide B-Induced Apoptosis in MCF-7 Breast Cancer Cells
por: Chan, Wen-Hsiung
Publicado: (2007)

Econazole Nitrate Induces Apoptosis in MCF-7 Cells via Mitochondrial and Caspase Pathways
por: Sun, Juan, et al.
Publicado: (2014)

Mechanism of EGCG promoting apoptosis of MCF-7 cell line in human breast cancer
por: Huang, Chao-You, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ijhum7ja438clu8rpt139bjj4v