CellProfiler Analyst: data exploration and analysis software for complex image-based screens

BACKGROUND: Image-based screens can produce hundreds of measured features for each of hundreds of millions of individual cells in a single experiment. RESULTS: Here, we describe CellProfiler Analyst, open-source software for the interactive exploration and analysis of multidimensional data, particul...

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Detalles Bibliográficos
Autores principales: Jones, Thouis R, Kang, In Han, Wheeler, Douglas B, Lindquist, Robert A, Papallo, Adam, Sabatini, David M, Golland, Polina, Carpenter, Anne E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614436/
https://www.ncbi.nlm.nih.gov/pubmed/19014601
http://dx.doi.org/10.1186/1471-2105-9-482
Descripción
Sumario:BACKGROUND: Image-based screens can produce hundreds of measured features for each of hundreds of millions of individual cells in a single experiment. RESULTS: Here, we describe CellProfiler Analyst, open-source software for the interactive exploration and analysis of multidimensional data, particularly data from high-throughput, image-based experiments. CONCLUSION: The system enables interactive data exploration for image-based screens and automated scoring of complex phenotypes that require combinations of multiple measured features per cell.

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