Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis

Many essential transcription factors have conserved roles in regulating biological programs, yet their genomic occupancy can diverge significantly. A new study demonstrates that such variations are primarily due to cis-regulatory sequences, rather than differences between the regulators or nuclear e...

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Detalles Bibliográficos
Autores principales: Zinzen, Robert P, Furlong, Eileen EM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614484/
https://www.ncbi.nlm.nih.gov/pubmed/19012800
http://dx.doi.org/10.1186/gb-2008-9-11-240
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author Zinzen, Robert P
Furlong, Eileen EM
author_facet Zinzen, Robert P
Furlong, Eileen EM
author_sort Zinzen, Robert P
collection PubMed
description Many essential transcription factors have conserved roles in regulating biological programs, yet their genomic occupancy can diverge significantly. A new study demonstrates that such variations are primarily due to cis-regulatory sequences, rather than differences between the regulators or nuclear environments.
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spelling pubmed-26144842009-11-04 Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis Zinzen, Robert P Furlong, Eileen EM Genome Biol Minireview Many essential transcription factors have conserved roles in regulating biological programs, yet their genomic occupancy can diverge significantly. A new study demonstrates that such variations are primarily due to cis-regulatory sequences, rather than differences between the regulators or nuclear environments. BioMed Central 2008 2008-11-04 /pmc/articles/PMC2614484/ /pubmed/19012800 http://dx.doi.org/10.1186/gb-2008-9-11-240 Text en Copyright © 2008 BioMed Central Ltd
spellingShingle Minireview
Zinzen, Robert P
Furlong, Eileen EM
Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis
title Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis
title_full Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis
title_fullStr Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis
title_full_unstemmed Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis
title_short Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis
title_sort divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614484/
https://www.ncbi.nlm.nih.gov/pubmed/19012800
http://dx.doi.org/10.1186/gb-2008-9-11-240
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