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A gene signature of loss of oestrogen receptor (ER) function and oxidative stress links ER-positive breast tumours with an absent progesterone receptor and a poor prognosis

Prognostic gene signatures like the wound and hypoxia signature differ by assumptions of cellular growth. Although gene signatures show little overlap, they also track within the group of luminal breast tumours those with a high proliferation and poor prognosis. Oxidative stress is another assumptio...

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Detalles Bibliográficos
Autores principales: Neven, Patrick, Van Gorp, Toon, Deraedt, Karen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614504/
https://www.ncbi.nlm.nih.gov/pubmed/18828867
http://dx.doi.org/10.1186/bcr2135

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