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Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours

INTRODUCTION: Expression of the putative Wnt signalling inhibitor Dickkopf-3 (DKK3) is frequently lost in human cancer tissues because of aberrant 5'-cytosine methylation within the DKK3 gene promoter. Since other Wnt signalling inhibitors have been reported to be targets of epigenetic inactiva...

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Detalles Bibliográficos
Autores principales:	Veeck, Jürgen, Bektas, Nuran, Hartmann, Arndt, Kristiansen, Glen, Heindrichs, Uwe, Knüchel, Ruth, Dahl, Edgar
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614517/ https://www.ncbi.nlm.nih.gov/pubmed/18826564 http://dx.doi.org/10.1186/bcr2151

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