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Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer

The widespread introduction of high throughput RNA interference screening technology has revealed tumour drug sensitivity pathways to common cytotoxics such as paclitaxel, doxorubicin and 5-fluorouracil, targeted agents such as trastuzumab and inhibitors of AKT and Poly(ADP-ribose) polymerase (PARP)...

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Detalles Bibliográficos
Autores principales:	Swanton, Charles, Szallasi, Zoltan, Brenton, James D, Downward, Julian
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614525/ https://www.ncbi.nlm.nih.gov/pubmed/18986507 http://dx.doi.org/10.1186/bcr2159

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