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Divergent Effects of PERK and IRE1 Signaling on Cell Viability

Protein misfolding in the endoplasmic reticulum (ER) activates a set of intracellular signaling pathways, collectively termed the Unfolded Protein Response (UPR). UPR signaling promotes cell survival by reducing misfolded protein levels. If homeostasis cannot be restored, UPR signaling promotes cell...

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Detalles Bibliográficos
Autores principales:	Lin, Jonathan H., Li, Han, Zhang, Yuhong, Ron, David, Walter, Peter
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614882/ https://www.ncbi.nlm.nih.gov/pubmed/19137072 http://dx.doi.org/10.1371/journal.pone.0004170

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