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Recent developments and strategies in pediatric pharmacology research in the USA

Research in pediatric pharmacology has undergone major changes in the last ten years, with an expansion in both publicly and privately funded activities. A number of pharmacokinetics studies and multi-site controlled efficacy trials have been conducted, so that treatment of children and adolescents...

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Autor principal: Vitiello, Benedetto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614962/
https://www.ncbi.nlm.nih.gov/pubmed/19063721
http://dx.doi.org/10.1186/1753-2000-2-36
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author Vitiello, Benedetto
author_facet Vitiello, Benedetto
author_sort Vitiello, Benedetto
collection PubMed
description Research in pediatric pharmacology has undergone major changes in the last ten years, with an expansion in both publicly and privately funded activities. A number of pharmacokinetics studies and multi-site controlled efficacy trials have been conducted, so that treatment of children and adolescents can now be better informed and evidence-based. Regulatory financial incentives to industry in return for studies on drugs still covered by patent exclusivity have resulted in a substantial increase in pediatric research funded by pharmaceutical companies. In parallel, public funding has supported research on off-patent medications and other clinical important aspects of treatment, such as comparisons between active treatments, including non-pharmacological interventions. With greater interest by industry in pediatric research, the role of government funding agencies has been redefined to avoid duplication and ensure better integration of efforts and utilization of resources. The present review discusses some of the recent developments in pediatric pharmacology with focus on psychiatric medications.
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spelling pubmed-26149622009-01-08 Recent developments and strategies in pediatric pharmacology research in the USA Vitiello, Benedetto Child Adolesc Psychiatry Ment Health Review Research in pediatric pharmacology has undergone major changes in the last ten years, with an expansion in both publicly and privately funded activities. A number of pharmacokinetics studies and multi-site controlled efficacy trials have been conducted, so that treatment of children and adolescents can now be better informed and evidence-based. Regulatory financial incentives to industry in return for studies on drugs still covered by patent exclusivity have resulted in a substantial increase in pediatric research funded by pharmaceutical companies. In parallel, public funding has supported research on off-patent medications and other clinical important aspects of treatment, such as comparisons between active treatments, including non-pharmacological interventions. With greater interest by industry in pediatric research, the role of government funding agencies has been redefined to avoid duplication and ensure better integration of efforts and utilization of resources. The present review discusses some of the recent developments in pediatric pharmacology with focus on psychiatric medications. BioMed Central 2008-12-08 /pmc/articles/PMC2614962/ /pubmed/19063721 http://dx.doi.org/10.1186/1753-2000-2-36 Text en Copyright © 2008 Vitiello; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Vitiello, Benedetto
Recent developments and strategies in pediatric pharmacology research in the USA
title Recent developments and strategies in pediatric pharmacology research in the USA
title_full Recent developments and strategies in pediatric pharmacology research in the USA
title_fullStr Recent developments and strategies in pediatric pharmacology research in the USA
title_full_unstemmed Recent developments and strategies in pediatric pharmacology research in the USA
title_short Recent developments and strategies in pediatric pharmacology research in the USA
title_sort recent developments and strategies in pediatric pharmacology research in the usa
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614962/
https://www.ncbi.nlm.nih.gov/pubmed/19063721
http://dx.doi.org/10.1186/1753-2000-2-36
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