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Lung adenocarcinoma presenting as obstructive jaundice: a case report and review of literature
BACKGROUND: Lung cancer is known to metastasize to the pancreas with several case reports found in the literature, however, most patients are at an advanced stage and receive palliative treatment. CASE PRESENTATION: We describe the case of a 56 year old male patient who presented with a picture of o...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615008/ https://www.ncbi.nlm.nih.gov/pubmed/19014447 http://dx.doi.org/10.1186/1477-7819-6-120 |
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author | Pericleous, Stephanos Mukherjee, Samrat Hutchins, Robert R |
author_facet | Pericleous, Stephanos Mukherjee, Samrat Hutchins, Robert R |
author_sort | Pericleous, Stephanos |
collection | PubMed |
description | BACKGROUND: Lung cancer is known to metastasize to the pancreas with several case reports found in the literature, however, most patients are at an advanced stage and receive palliative treatment. CASE PRESENTATION: We describe the case of a 56 year old male patient who presented with a picture of obstructive jaundice. Investigations revealed an obstructing lesion in the pancreas and a further lesion in the lung with benign appearances. The patient underwent a pancreatectomy and, unexpectedly, the histology of the resected specimen demonstrated metastatic adenocarcinoma of bronchogenic origin. He was referred to a cardiothoracic team who proceeded to resect the patient's thoracic lesion before administration of adjuvant chemotherapy. The patient was reviewed 18 months post operatively and remains symptom free with no clinical or radiological evidence of recurrence. We were unable to identify any previous case reports (of lung adenocarcinoma) with such a presentation which were ultimately treated with resection of both lesions. CONCLUSION: Similar situations are bound to arise again in the future and we believe that this report could demonstrate that there is a case for aggressive surgical management in a highly selected group of patients: those with NSCLC and a synchronous solitary pancreatic deposit. |
format | Text |
id | pubmed-2615008 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-26150082009-01-08 Lung adenocarcinoma presenting as obstructive jaundice: a case report and review of literature Pericleous, Stephanos Mukherjee, Samrat Hutchins, Robert R World J Surg Oncol Review BACKGROUND: Lung cancer is known to metastasize to the pancreas with several case reports found in the literature, however, most patients are at an advanced stage and receive palliative treatment. CASE PRESENTATION: We describe the case of a 56 year old male patient who presented with a picture of obstructive jaundice. Investigations revealed an obstructing lesion in the pancreas and a further lesion in the lung with benign appearances. The patient underwent a pancreatectomy and, unexpectedly, the histology of the resected specimen demonstrated metastatic adenocarcinoma of bronchogenic origin. He was referred to a cardiothoracic team who proceeded to resect the patient's thoracic lesion before administration of adjuvant chemotherapy. The patient was reviewed 18 months post operatively and remains symptom free with no clinical or radiological evidence of recurrence. We were unable to identify any previous case reports (of lung adenocarcinoma) with such a presentation which were ultimately treated with resection of both lesions. CONCLUSION: Similar situations are bound to arise again in the future and we believe that this report could demonstrate that there is a case for aggressive surgical management in a highly selected group of patients: those with NSCLC and a synchronous solitary pancreatic deposit. BioMed Central 2008-11-11 /pmc/articles/PMC2615008/ /pubmed/19014447 http://dx.doi.org/10.1186/1477-7819-6-120 Text en Copyright © 2008 Pericleous et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Pericleous, Stephanos Mukherjee, Samrat Hutchins, Robert R Lung adenocarcinoma presenting as obstructive jaundice: a case report and review of literature |
title | Lung adenocarcinoma presenting as obstructive jaundice: a case report and review of literature |
title_full | Lung adenocarcinoma presenting as obstructive jaundice: a case report and review of literature |
title_fullStr | Lung adenocarcinoma presenting as obstructive jaundice: a case report and review of literature |
title_full_unstemmed | Lung adenocarcinoma presenting as obstructive jaundice: a case report and review of literature |
title_short | Lung adenocarcinoma presenting as obstructive jaundice: a case report and review of literature |
title_sort | lung adenocarcinoma presenting as obstructive jaundice: a case report and review of literature |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615008/ https://www.ncbi.nlm.nih.gov/pubmed/19014447 http://dx.doi.org/10.1186/1477-7819-6-120 |
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