Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5Y

BACKGROUND: SH-SY5Y cells exhibit a neuronal phenotype when treated with all-trans retinoic acid (RA), but the molecular mechanism of activation in the signalling pathway mediated by phosphatidylinositol 3-kinase (PI3K) is unclear. To investigate this mechanism, we compared the gene expression profi...

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Detalles Bibliográficos
Autores principales: Nishida, Yuichiro, Adati, Naoki, Ozawa, Ritsuko, Maeda, Aasami, Sakaki, Yoshiyuki, Takeda, Tadayuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615028/
https://www.ncbi.nlm.nih.gov/pubmed/18957096
http://dx.doi.org/10.1186/1756-0500-1-95

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