Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt–β-catenin and Wnt–RhoA–Rac1 pathways

Mutations in bone morphogenetic protein (BMP) receptor II (BMPRII) are associated with pulmonary artery endothelial cell (PAEC) apoptosis and the loss of small vessels seen in idiopathic pulmonary arterial hypertension. Given the low penetrance of BMPRII mutations, abnormalities in other converging...

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Detalles Bibliográficos
Autores principales: de Jesus Perez, Vinicio A., Alastalo, Tero-Pekka, Wu, Jenny C., Axelrod, Jeffrey D., Cooke, John P., Amieva, Manuel, Rabinovitch, Marlene
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615088/
https://www.ncbi.nlm.nih.gov/pubmed/19139264
http://dx.doi.org/10.1083/jcb.200806049

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