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The nuclear export factor Xpo1p targets Mad1p to kinetochores in yeast

Nuclear pore complexes (NPCs) mediate all nucleocytoplasmic traffic and provide docking sites for the spindle assembly checkpoint (SAC) protein Mad1p. Upon SAC activation, Mad1p is recruited onto kinetochores and rapidly cycles between NPCs and kinetochores. We examined the mechanism of Mad1p moveme...

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Detalles Bibliográficos
Autores principales: Scott, Robert J., Cairo, Lucas V., Van de Vosse, David W., Wozniak, Richard W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615093/
https://www.ncbi.nlm.nih.gov/pubmed/19139260
http://dx.doi.org/10.1083/jcb.200804098