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DNA Polymerase δ Is Required for Early Mammalian Embryogenesis

BACKGROUND: In eukaryotic cells, DNA polymerase δ (Polδ), whose catalytic subunit p125 is encoded in the Pold1 gene, plays a central role in chromosomal DNA replication, repair, and recombination. However, the physiological role of the Polδ in mammalian development has not been thoroughly investigat...

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Detalles Bibliográficos
Autores principales:	Uchimura, Arikuni, Hidaka, Yuko, Hirabayashi, Takahiro, Hirabayashi, Masumi, Yagi, Takeshi
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615215/ https://www.ncbi.nlm.nih.gov/pubmed/19145245 http://dx.doi.org/10.1371/journal.pone.0004184

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