The PtdIns 3-Kinase/Akt Pathway Regulates Macrophage-Mediated ADCC against B Cell Lymphoma

Macrophages are important effectors in the clearance of antibody-coated tumor cells. However, the signaling pathways that regulate macrophage-induced ADCC are poorly defined. To understand the regulation of macrophage-mediated ADCC, we used human B cell lymphoma coated with Rituximab as the tumor ta...

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Detalles Bibliográficos
Autores principales: Joshi, Trupti, Ganesan, Latha P., Cheney, Carolyn, Ostrowski, Michael C., Muthusamy, Natarajan, Byrd, John C., Tridandapani, Susheela
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615217/
https://www.ncbi.nlm.nih.gov/pubmed/19148288
http://dx.doi.org/10.1371/journal.pone.0004208

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