Cargando…

Disruption of a Plasmodium falciparum cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis

Phosphodiesterase (PDE) and guanylyl cyclase (GC) enzymes are key components of the cGMP signalling pathway and are encoded in the genome of Plasmodium falciparum. Here we investigate the role of specific GC and PDE isoforms in gamete formation – a process that is essential for malaria transmission...

Descripción completa

Detalles Bibliográficos
Autores principales:	Taylor, Cathy J, McRobert, Louisa, Baker, David A
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2008
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615252/ https://www.ncbi.nlm.nih.gov/pubmed/18452584 http://dx.doi.org/10.1111/j.1365-2958.2008.06267.x

Ejemplares similares

Gametogenesis in Malaria Parasites Is Mediated by the cGMP-Dependent Protein Kinase
por: McRobert, Louisa, et al.
Publicado: (2008)

A developmental defect in Plasmodium falciparum male gametogenesis
Publicado: (1996)

Plasmodium falciparum CRK5 Is Critical for Male Gametogenesis and Infection of the Mosquito
por: Kumar, Sudhir, et al.
Publicado: (2022)

Cyclic nucleotide specific phosphodiesterases of Leishmania major
por: Johner, Andrea, et al.
Publicado: (2006)

Cyclic nucleotide phosphodiesterases – 40 years of progress
por: Beavo, Joseph A, et al.
Publicado: (2009)

Cyclic nucleotide phosphodiesterase 1 and vascular aging
por: Yan, Chen
Publicado: (2015)

Cryogenically preserved RBCs support gametocytogenesis of Plasmodium falciparum in vitro and gametogenesis in mosquitoes
por: Pathak, Ashutosh K., et al.
Publicado: (2018)

PfMAP-2 is essential for male gametogenesis in the malaria parasite Plasmodium falciparum
por: Hitz, Eva, et al.
Publicado: (2020)

Cyclic AMP compartments and signaling specificity: Role of cyclic nucleotide phosphodiesterases
por: Conti, Marco, et al.
Publicado: (2014)

Editorial: Cyclic Nucleotide Phosphodiesterases (PDEs) in Immune Regulation and Inflammation
por: Brocke, Stefan, et al.
Publicado: (2022)

Role of Cyclic Nucleotide Phosphodiesterases in Inner Ear and Hearing
por: Mittal, Rahul, et al.
Publicado: (2017)

Plasmodium falciparum Calcium-Dependent Protein Kinase 4 is Critical for Male Gametogenesis and Transmission to the Mosquito Vector
por: Kumar, Sudhir, et al.
Publicado: (2021)

Phosphodiesterases Maintain Signaling Fidelity via Compartmentalization of Cyclic Nucleotides
por: Lomas, Oliver, et al.
Publicado: (2014)

Regulation of the renin-angiotensin-aldosterone system by cyclic nucleotides and phosphodiesterases
por: Gambaryan, Stepan, et al.
Publicado: (2023)

Gametogenesis in Plasmodium: Delving Deeper to Connect the Dots
por: Dash, Manoswini, et al.
Publicado: (2022)

Expression and Regulation of Cyclic Nucleotide Phosphodiesterases in Human and Rat Pancreatic Islets
por: Heimann, Emilia, et al.
Publicado: (2010)

Cardiac Cyclic Nucleotide Phosphodiesterases: Roles and Therapeutic Potential in Heart Failure
por: Preedy, Michael E. J.
Publicado: (2020)

Cyclic Nucleotide Phosphodiesterases in Alcohol Use Disorders: Involving Gut Microbiota
por: Hou, Xueqin, et al.
Publicado: (2022)

To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?
por: Zheng, Yang, et al.
Publicado: (2023)

Modulation of Compartmentalised Cyclic Nucleotide Signalling via Local Inhibition of Phosphodiesterase Activity
por: Brescia, Marcella, et al.
Publicado: (2016)

Once upon a Testis: The Tale of Cyclic Nucleotide Phosphodiesterase in Testicular Cancers
por: Campolo, Federica, et al.
Publicado: (2023)

Analysis of Substrate Specificity and Kinetics of Cyclic Nucleotide Phosphodiesterases with N’-Methylanthraniloyl-Substituted Purine and Pyrimidine 3′,5′-Cyclic Nucleotides by Fluorescence Spectrometry
por: Reinecke, Daniel, et al.
Publicado: (2013)

Dissecting The role of Plasmodium metacaspase-2 in malaria gametogenesis and sporogony
por: Kumari, Vandana, et al.
Publicado: (2022)

Alterations in cyclic nucleotide phosphodiesterase activities in omental and subcutaneous adipose tissues in human obesity
por: Omar, B, et al.
Publicado: (2011)

2’,3’-Cyclic Nucleotide 3’-Phosphodiesterases Inhibit Hepatitis B Virus Replication
por: Ma, Hui, et al.
Publicado: (2013)

Identification and Localization of the Cyclic Nucleotide Phosphodiesterase 10A in Bovine Testis and Mature Spermatozoa
por: Goupil, Serge, et al.
Publicado: (2016)

The Functions of Mitochondrial 2′,3′-Cyclic Nucleotide-3′-Phosphodiesterase and Prospects for Its Future
por: Olga, Krestinina, et al.
Publicado: (2020)

The Phosphodiesterase Inhibitor Tadalafil Promotes Splenic Retention of Plasmodium falciparum Gametocytes in Humanized Mice
por: Barbieri, Daniela, et al.
Publicado: (2022)

CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE : An Early Defect in Inherited Retinal Degeneration of C3H Mice
por: Schmidt, Susan Y., et al.
Publicado: (1973)

Mechanisms of Cyclic Nucleotide Phosphodiesterases in Modulating T Cell Responses in Murine Graft-versus-Host Disease
por: Weber, Michael, et al.
Publicado: (2013)

Investigation of an (18)F-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A
por: Schröder, Susann, et al.
Publicado: (2018)

The Endocrine Function of the Heart: Physiology and Involvements of Natriuretic Peptides and Cyclic Nucleotide Phosphodiesterases in Heart Failure
por: Lugnier, Claire, et al.
Publicado: (2019)

Cellular Redox Metabolism Is Modulated by the Distinct Localization of Cyclic Nucleotide Phosphodiesterase 5A Isoforms
por: Cardarelli, Silvia, et al.
Publicado: (2022)

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B
por: Johanns, M., et al.
Publicado: (2016)

In Vivo Assessment of Local Phosphodiesterase Activity Using Tailored Cyclic Nucleotide–Gated Channels as Camp Sensors
por: Rich, Thomas C., et al.
Publicado: (2001)

Function of calmodulin in postsynaptic densities. I. Presence of a calmodulin-activatable cyclic nucleotide phosphodiesterase activity
Publicado: (1981)

Myelin 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation
por: Myllykoski, Matti, et al.
Publicado: (2012)

Determinants of ligand binding and catalytic activity in the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase
por: Raasakka, Arne, et al.
Publicado: (2015)

Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012
por: Schröder, Susann, et al.
Publicado: (2016)

An essential role of Plasmodium berghei kinesin 8 in axoneme assembly and male gametogenesis
por: Depoix, D, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_vb9pv12vgrotoe9qcj0ihdesjk