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Disruption of a Plasmodium falciparum cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis

Phosphodiesterase (PDE) and guanylyl cyclase (GC) enzymes are key components of the cGMP signalling pathway and are encoded in the genome of Plasmodium falciparum. Here we investigate the role of specific GC and PDE isoforms in gamete formation – a process that is essential for malaria transmission...

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Detalles Bibliográficos
Autores principales:	Taylor, Cathy J, McRobert, Louisa, Baker, David A
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2008
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615252/ https://www.ncbi.nlm.nih.gov/pubmed/18452584 http://dx.doi.org/10.1111/j.1365-2958.2008.06267.x

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