Rituximab-CHOP Induced Interstitial Pneumonitis in Patients with Disseminated Extranodal Marginal Zone B Cell Lymphoma

A 69-year-old male was diagnosed in February 2004 with stage IV extranodal marginal zone B cell lymphoma involving the mediastinal nodes, lung parenchyma and bone marrow with high LDH. Shortness of breath developed following the 5th course of Rituximab-CHOP chemotherapy (cyclophosphamide, Vincristin...

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Autores principales: Kim, Kwang Min, Kim, Ho-Cheol, Jeon, Kyung-Nyeo, Kim, Hoon-Gu, Kang, Jung Hun, Hahm, Jong Ryeal, Lee, Gyeong-Won
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615269/
https://www.ncbi.nlm.nih.gov/pubmed/18306483
http://dx.doi.org/10.3349/ymj.2008.49.1.155
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author Kim, Kwang Min
Kim, Ho-Cheol
Jeon, Kyung-Nyeo
Kim, Hoon-Gu
Kang, Jung Hun
Hahm, Jong Ryeal
Lee, Gyeong-Won
author_facet Kim, Kwang Min
Kim, Ho-Cheol
Jeon, Kyung-Nyeo
Kim, Hoon-Gu
Kang, Jung Hun
Hahm, Jong Ryeal
Lee, Gyeong-Won
author_sort Kim, Kwang Min
collection PubMed
description A 69-year-old male was diagnosed in February 2004 with stage IV extranodal marginal zone B cell lymphoma involving the mediastinal nodes, lung parenchyma and bone marrow with high LDH. Shortness of breath developed following the 5th course of Rituximab-CHOP chemotherapy (cyclophosphamide, Vincristine, Doxorubicin, Prednisolone). Bronchoscopy guided transbronchial lung biopsy revealed interstitial thickening and type II pneumocyte activation, compatible with interstitial pneumonitis. After treatment with prednisolone a complete resolution of the dyspnea was observed. The patient was well on routine follow-up at the outpatient clinic, with no progression of lymphoma or interstitial pneumonitis.
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spelling pubmed-26152692009-02-02 Rituximab-CHOP Induced Interstitial Pneumonitis in Patients with Disseminated Extranodal Marginal Zone B Cell Lymphoma Kim, Kwang Min Kim, Ho-Cheol Jeon, Kyung-Nyeo Kim, Hoon-Gu Kang, Jung Hun Hahm, Jong Ryeal Lee, Gyeong-Won Yonsei Med J Case Report A 69-year-old male was diagnosed in February 2004 with stage IV extranodal marginal zone B cell lymphoma involving the mediastinal nodes, lung parenchyma and bone marrow with high LDH. Shortness of breath developed following the 5th course of Rituximab-CHOP chemotherapy (cyclophosphamide, Vincristine, Doxorubicin, Prednisolone). Bronchoscopy guided transbronchial lung biopsy revealed interstitial thickening and type II pneumocyte activation, compatible with interstitial pneumonitis. After treatment with prednisolone a complete resolution of the dyspnea was observed. The patient was well on routine follow-up at the outpatient clinic, with no progression of lymphoma or interstitial pneumonitis. Yonsei University College of Medicine 2008-02-29 2008-02-20 /pmc/articles/PMC2615269/ /pubmed/18306483 http://dx.doi.org/10.3349/ymj.2008.49.1.155 Text en Copyright © 2008 The Yonsei University College of Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Kwang Min
Kim, Ho-Cheol
Jeon, Kyung-Nyeo
Kim, Hoon-Gu
Kang, Jung Hun
Hahm, Jong Ryeal
Lee, Gyeong-Won
Rituximab-CHOP Induced Interstitial Pneumonitis in Patients with Disseminated Extranodal Marginal Zone B Cell Lymphoma
title Rituximab-CHOP Induced Interstitial Pneumonitis in Patients with Disseminated Extranodal Marginal Zone B Cell Lymphoma
title_full Rituximab-CHOP Induced Interstitial Pneumonitis in Patients with Disseminated Extranodal Marginal Zone B Cell Lymphoma
title_fullStr Rituximab-CHOP Induced Interstitial Pneumonitis in Patients with Disseminated Extranodal Marginal Zone B Cell Lymphoma
title_full_unstemmed Rituximab-CHOP Induced Interstitial Pneumonitis in Patients with Disseminated Extranodal Marginal Zone B Cell Lymphoma
title_short Rituximab-CHOP Induced Interstitial Pneumonitis in Patients with Disseminated Extranodal Marginal Zone B Cell Lymphoma
title_sort rituximab-chop induced interstitial pneumonitis in patients with disseminated extranodal marginal zone b cell lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615269/
https://www.ncbi.nlm.nih.gov/pubmed/18306483
http://dx.doi.org/10.3349/ymj.2008.49.1.155
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