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The Effect of HIF-1α siRNA on Growth and Chemosensitivity of Mia-paca Cell Line
PURPOSE: Hypoxia-inducible factor-1α (HIF-1α) primarily mediates the hypoxic response. HIF-1α induction by various stimuli contributes to cell proliferation and survival. To investigate the effect of HIF-1α, we used small interfering RNA (siRNA), and expected that cell apoptosis and sensitivity to c...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Yonsei University College of Medicine
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615320/ https://www.ncbi.nlm.nih.gov/pubmed/18452268 http://dx.doi.org/10.3349/ymj.2008.49.2.295 |