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Diagnosis of Pseudoangiomatous Stromal Hyperplasia of the Breast: Ultrasonography Findings and Different Biopsy Methods

PURPOSE: Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a rare, benign condition that can be mistaken as a fibroadenoma on an ultrasound examination or as a low-grade angiosarcoma on a histological examination. The objective of this study was to evaluate the ultrasound features and to...

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Autores principales: Choi, Yoon Jung, Ko, Eun Young, Kook, Shinho
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615356/
https://www.ncbi.nlm.nih.gov/pubmed/18972596
http://dx.doi.org/10.3349/ymj.2008.49.5.757
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author Choi, Yoon Jung
Ko, Eun Young
Kook, Shinho
author_facet Choi, Yoon Jung
Ko, Eun Young
Kook, Shinho
author_sort Choi, Yoon Jung
collection PubMed
description PURPOSE: Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a rare, benign condition that can be mistaken as a fibroadenoma on an ultrasound examination or as a low-grade angiosarcoma on a histological examination. The objective of this study was to evaluate the ultrasound features and to present biopsy methods to correctly identify PASH. PATIENTS AND METHODS: We retrospectively reviewed the data of 55 women who were diagnosed with PASH of the breast. Ultrasound features were evaluated according to the Breast Imaging Reporting and Data System (BI-RADS; American College of Radiology). The diagnostic ability of different biopsy methods such as core needle biopsy, vacuum-assisted biopsy and excisional biopsy were analyzed with the final histopathological results of surgical specimens. RESULTS: PASH presented as a circumscribed solid mass, with hypoechoic texture with or without heterogeneity, and a parallel orientation. The features of small, internal cysts or vascular channels and no calcifications can be used to differentiate the lesions from fibroadenomas. A core needle biopsy misdiagnosed PASH in 13 cases out of 28 cases and vacuum-assisted biopsy correctly identified PASH in all 3 cases. CONCLUSION: Ultrasound features of PASH should be noted when performing a biopsy. For inconclusive cases of PASH, an excisional biopsy followed by an initial core biopsy should be performed.
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spelling pubmed-26153562009-02-02 Diagnosis of Pseudoangiomatous Stromal Hyperplasia of the Breast: Ultrasonography Findings and Different Biopsy Methods Choi, Yoon Jung Ko, Eun Young Kook, Shinho Yonsei Med J Original Article PURPOSE: Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a rare, benign condition that can be mistaken as a fibroadenoma on an ultrasound examination or as a low-grade angiosarcoma on a histological examination. The objective of this study was to evaluate the ultrasound features and to present biopsy methods to correctly identify PASH. PATIENTS AND METHODS: We retrospectively reviewed the data of 55 women who were diagnosed with PASH of the breast. Ultrasound features were evaluated according to the Breast Imaging Reporting and Data System (BI-RADS; American College of Radiology). The diagnostic ability of different biopsy methods such as core needle biopsy, vacuum-assisted biopsy and excisional biopsy were analyzed with the final histopathological results of surgical specimens. RESULTS: PASH presented as a circumscribed solid mass, with hypoechoic texture with or without heterogeneity, and a parallel orientation. The features of small, internal cysts or vascular channels and no calcifications can be used to differentiate the lesions from fibroadenomas. A core needle biopsy misdiagnosed PASH in 13 cases out of 28 cases and vacuum-assisted biopsy correctly identified PASH in all 3 cases. CONCLUSION: Ultrasound features of PASH should be noted when performing a biopsy. For inconclusive cases of PASH, an excisional biopsy followed by an initial core biopsy should be performed. Yonsei University College of Medicine 2008-10-31 2008-10-31 /pmc/articles/PMC2615356/ /pubmed/18972596 http://dx.doi.org/10.3349/ymj.2008.49.5.757 Text en Copyright © 2008 The Yonsei University College of Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Choi, Yoon Jung
Ko, Eun Young
Kook, Shinho
Diagnosis of Pseudoangiomatous Stromal Hyperplasia of the Breast: Ultrasonography Findings and Different Biopsy Methods
title Diagnosis of Pseudoangiomatous Stromal Hyperplasia of the Breast: Ultrasonography Findings and Different Biopsy Methods
title_full Diagnosis of Pseudoangiomatous Stromal Hyperplasia of the Breast: Ultrasonography Findings and Different Biopsy Methods
title_fullStr Diagnosis of Pseudoangiomatous Stromal Hyperplasia of the Breast: Ultrasonography Findings and Different Biopsy Methods
title_full_unstemmed Diagnosis of Pseudoangiomatous Stromal Hyperplasia of the Breast: Ultrasonography Findings and Different Biopsy Methods
title_short Diagnosis of Pseudoangiomatous Stromal Hyperplasia of the Breast: Ultrasonography Findings and Different Biopsy Methods
title_sort diagnosis of pseudoangiomatous stromal hyperplasia of the breast: ultrasonography findings and different biopsy methods
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615356/
https://www.ncbi.nlm.nih.gov/pubmed/18972596
http://dx.doi.org/10.3349/ymj.2008.49.5.757
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