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Therapeutic Modulation of Apoptosis: Targeting the BCL-2 Family at the Interface of the Mitochondrial Membrane

A vast portion of human disease results when the process of apoptosis is defective. Disorders resulting from inappropriate cell death range from autoimmune and neurodegenerative conditions to heart disease. Conversely, prevention of apoptosis is the hallmark of cancer and confounds the efficacy of c...

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Detalles Bibliográficos
Autores principales: Nemec, Kathleen N., Khaled, Annette R.
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615374/
https://www.ncbi.nlm.nih.gov/pubmed/18972587
http://dx.doi.org/10.3349/ymj.2008.49.5.689