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Regulation of growth and survival of activated T cells by cell-transducing inhibitors of Ras
We describe the development of cell-penetrating inhibitors of Ras and study their ability to inhibit T cell activation. The inhibitors transduced T cells in a time and concentration-dependent manner and interacted with endogenous Ras. Anti-CD3/CD28-activated cells when treated with the inhibitors, e...
Autores principales: | Malik, Nasser M., Gilroy, Derek W., Kabouridis, Panagiotis S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science B.V
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615550/ https://www.ncbi.nlm.nih.gov/pubmed/19063885 http://dx.doi.org/10.1016/j.febslet.2008.11.042 |
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