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Involvement of the TPR2 subdomain movement in the activities of ϕ29 DNA polymerase

The polymerization domain of ϕ29 DNA polymerase acquires a toroidal shape by means of an arch-like structure formed by the specific insertion TPR2 (Terminal Protein Region 2) and the thumb subdomain. TPR2 is connected to the fingers and palm subdomains through flexible regions, suggesting that it ca...

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Detalles Bibliográficos
Autores principales:	Rodríguez, Irene, Lázaro, José María, Salas, Margarita, de Vega, Miguel
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615600/ https://www.ncbi.nlm.nih.gov/pubmed/19033368 http://dx.doi.org/10.1093/nar/gkn928

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