Analysis of re-replication from deregulated origin licensing by DNA fiber spreading

A major challenge each human cell-division cycle is to ensure that DNA replication origins do not initiate more than once, a phenomenon known as re-replication. Acute deregulation of replication control ultimately causes extensive DNA damage, cell-cycle checkpoint activation and cell death whereas m...

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Detalles Bibliográficos
Autores principales: Dorn, Elizabeth S., Chastain, Paul D., Hall, Jonathan R., Cook, Jeanette Gowen
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615611/
https://www.ncbi.nlm.nih.gov/pubmed/19010964
http://dx.doi.org/10.1093/nar/gkn912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615611/
https://www.ncbi.nlm.nih.gov/pubmed/19010964
http://dx.doi.org/10.1093/nar/gkn912

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