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A flow cytometry-based screen for synthetic riboswitches

Riboswitches regulate gene expression through direct, small molecule–mRNA interactions. The creation of new synthetic riboswitches from in vitro selected aptamers benefits from rapid, high-throughput methods for identifying switches capable of triggering dramatic changes in gene expression in the pr...

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Detalles Bibliográficos
Autores principales: Lynch, Sean A., Gallivan, Justin P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615613/
https://www.ncbi.nlm.nih.gov/pubmed/19033367
http://dx.doi.org/10.1093/nar/gkn924