Cargando…
Twist-1 regulates the miR-199a/214 cluster during development
MicroRNAs are known to regulate developmental processes but their mechanism of regulation remains largely uncharacterized. We show the transcription factor Twist-1 drives the expression of a 7.9-kb noncoding RNA transcript (from the Dynamin-3 gene intron) that encodes a miR-199a and miR-214 cluster....
Autores principales: | Lee, Youn-Bok, Bantounas, Ioannis, Lee, Do-Young, Phylactou, Leonidas, Caldwell, Maeve A., Uney, James B. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615617/ https://www.ncbi.nlm.nih.gov/pubmed/19029138 http://dx.doi.org/10.1093/nar/gkn920 |
Ejemplares similares
-
New twists of a TAIL: novel insights into the histone binding properties of a highly conserved PHD finger cluster within the MLR family of H3K4 mono-methyltransferases
por: Zraly, Claudia B, et al.
Publicado: (2023) -
How ‘arm-twisting’ by the inducer triggers activation of the MalT transcription factor, a typical signal transduction ATPase with numerous domains (STAND)
por: Danot, Olivier
Publicado: (2015) -
MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice
por: Cogoi, Susanna, et al.
Publicado: (2013) -
A histidine cluster determines YY1-compartmentalized coactivators and chromatin elements in phase-separated enhancer clusters
por: Wang, Wenmeng, et al.
Publicado: (2022) -
The three-dimensional architecture of Hox cluster silencing
por: Ferraiuolo, Maria A., et al.
Publicado: (2010)