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Aged B lymphocytes retain their ability to express surface markers but are dysfunctional in their proliferative capability during early activation events

BACKGROUND: Ageing is associated with dysfunction in the humoral response leading to decreased protection against infectious diseases. Defects in T cell function due to age have been well characterized but it is unclear if dysfunctions in antibody responses are due to deficiencies in a helper enviro...

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Detalles Bibliográficos
Autores principales: Blaeser, Anthony, McGlauchlen, Kiley, Vogel, Laura A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615744/
https://www.ncbi.nlm.nih.gov/pubmed/19014641
http://dx.doi.org/10.1186/1742-4933-5-15