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Aged B lymphocytes retain their ability to express surface markers but are dysfunctional in their proliferative capability during early activation events
BACKGROUND: Ageing is associated with dysfunction in the humoral response leading to decreased protection against infectious diseases. Defects in T cell function due to age have been well characterized but it is unclear if dysfunctions in antibody responses are due to deficiencies in a helper enviro...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615744/ https://www.ncbi.nlm.nih.gov/pubmed/19014641 http://dx.doi.org/10.1186/1742-4933-5-15 |