An infant with asymptomatic hepatic granuloma probably caused by bacillus Calmette-Guérin (BCG) vaccination found incidentally at autopsy: a case report

INTRODUCTION: Bacillus Calmette-Guérin (BCG) is an attenuated strain of Mycobacterium bovis. Usually, systemic complications due to BCG vaccination are quite rare. However, since BCG is a live vaccine, there is still a possibility that it may cause an infection. CASE PRESENTATION: Hepatic granuloma...

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Detalles Bibliográficos
Autores principales: Tajima, Yutaka, Takagi, Rie, Nakajima, Tamiko, Kominato, Yoshihiko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615765/
https://www.ncbi.nlm.nih.gov/pubmed/19019255
http://dx.doi.org/10.1186/1757-1626-1-337
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author Tajima, Yutaka
Takagi, Rie
Nakajima, Tamiko
Kominato, Yoshihiko
author_facet Tajima, Yutaka
Takagi, Rie
Nakajima, Tamiko
Kominato, Yoshihiko
author_sort Tajima, Yutaka
collection PubMed
description INTRODUCTION: Bacillus Calmette-Guérin (BCG) is an attenuated strain of Mycobacterium bovis. Usually, systemic complications due to BCG vaccination are quite rare. However, since BCG is a live vaccine, there is still a possibility that it may cause an infection. CASE PRESENTATION: Hepatic granuloma was found incidentally in an asymptomatic 5-month-old infant who was found dead in his bed. The probable cause of death was asphyxia due to milk aspiration into the lungs. The granuloma was composed of epithelioid histiocytes with frequent multinucleated Langhans-type giant cells and a small number of lymphocytes. CONCLUSION: The cause of the asymptomatic granuloma was not identified, but was considered likely due to BCG vaccination.
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spelling pubmed-26157652009-01-10 An infant with asymptomatic hepatic granuloma probably caused by bacillus Calmette-Guérin (BCG) vaccination found incidentally at autopsy: a case report Tajima, Yutaka Takagi, Rie Nakajima, Tamiko Kominato, Yoshihiko Cases J Case Report INTRODUCTION: Bacillus Calmette-Guérin (BCG) is an attenuated strain of Mycobacterium bovis. Usually, systemic complications due to BCG vaccination are quite rare. However, since BCG is a live vaccine, there is still a possibility that it may cause an infection. CASE PRESENTATION: Hepatic granuloma was found incidentally in an asymptomatic 5-month-old infant who was found dead in his bed. The probable cause of death was asphyxia due to milk aspiration into the lungs. The granuloma was composed of epithelioid histiocytes with frequent multinucleated Langhans-type giant cells and a small number of lymphocytes. CONCLUSION: The cause of the asymptomatic granuloma was not identified, but was considered likely due to BCG vaccination. BioMed Central 2008-11-20 /pmc/articles/PMC2615765/ /pubmed/19019255 http://dx.doi.org/10.1186/1757-1626-1-337 Text en Copyright © 2008 Tajima et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tajima, Yutaka
Takagi, Rie
Nakajima, Tamiko
Kominato, Yoshihiko
An infant with asymptomatic hepatic granuloma probably caused by bacillus Calmette-Guérin (BCG) vaccination found incidentally at autopsy: a case report
title An infant with asymptomatic hepatic granuloma probably caused by bacillus Calmette-Guérin (BCG) vaccination found incidentally at autopsy: a case report
title_full An infant with asymptomatic hepatic granuloma probably caused by bacillus Calmette-Guérin (BCG) vaccination found incidentally at autopsy: a case report
title_fullStr An infant with asymptomatic hepatic granuloma probably caused by bacillus Calmette-Guérin (BCG) vaccination found incidentally at autopsy: a case report
title_full_unstemmed An infant with asymptomatic hepatic granuloma probably caused by bacillus Calmette-Guérin (BCG) vaccination found incidentally at autopsy: a case report
title_short An infant with asymptomatic hepatic granuloma probably caused by bacillus Calmette-Guérin (BCG) vaccination found incidentally at autopsy: a case report
title_sort infant with asymptomatic hepatic granuloma probably caused by bacillus calmette-guérin (bcg) vaccination found incidentally at autopsy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615765/
https://www.ncbi.nlm.nih.gov/pubmed/19019255
http://dx.doi.org/10.1186/1757-1626-1-337
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