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Regulation of the Drosophila Apoptosome through Feedback Inhibition
Apoptosis is induced by caspases, which are members of the cysteine protease family 1. Caspases are synthesized as inactive zymogens and initiator caspases first gain activity by associating with an oligomeric complex of their adaptor proteins, such as the apoptosome 2,3. Activated initiator caspase...
Autores principales: | Shapiro, Peter J., Hsu, Hans H., Jung, Heekyung, Robbins, Edith S., Ryoo, Hyung Don |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2617731/ https://www.ncbi.nlm.nih.gov/pubmed/19011620 http://dx.doi.org/10.1038/ncb1803 |
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