IGFBP3 Colocalizes with and Regulates Hypocretin (Orexin)

BACKGROUND: The sleep disorder narcolepsy is caused by a vast reduction in neurons producing the hypocretin (orexin) neuropeptides. Based on the tight association with HLA, narcolepsy is believed to result from an autoimmune attack, but the cause of hypocretin cell loss is still unknown. We performe...

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Detalles Bibliográficos
Autores principales: Honda, Makoto, Eriksson, Krister S., Zhang, Shengwen, Tanaka, Susumu, Lin, Ling, Salehi, Ahmad, Hesla, Per Egil, Maehlen, Jan, Gaus, Stephanie E., Yanagisawa, Masashi, Sakurai, Takeshi, Taheri, Shahrad, Tsuchiya, Kuniaki, Honda, Yutaka, Mignot, Emmanuel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2617764/
https://www.ncbi.nlm.nih.gov/pubmed/19158946
http://dx.doi.org/10.1371/journal.pone.0004254

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