Lack of Association of Interferon Regulatory Factor 1 with Severe Malaria in Affected Child-Parental Trio Studies across Three African Populations

Interferon Regulatory Factor 1 (IRF-1) is a member of the IRF family of transcription factors, which have key and diverse roles in the gene-regulatory networks of the immune system. IRF-1 has been described as a critical mediator of IFN-gamma signalling and as the major player in driving TH1 type re...

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Detalles Bibliográficos
Autores principales: Mangano, Valentina D., Clark, Taane G., Auburn, Sarah, Campino, Susana, Diakite, Mahamadou, Fry, Andrew E., Green, Angela, Richardson, Anna, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Griffiths, Michael J., Newton, Charles, Peshu, Norbert, Williams, Thomas N., Marsh, Kevin, Molyneux, Malcolm E., Taylor, Terrie E., Modiano, David, Kwiatkowski, Dominic P., Rockett, Kirk A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621088/
https://www.ncbi.nlm.nih.gov/pubmed/19145247
http://dx.doi.org/10.1371/journal.pone.0004206

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