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Osteosarcoma of the larynx: a case report

BACKGROUND: We add a new rare illustrative case of osteosarcoma of the larynx to the literature. CASE PRESENTATION: The patient (man; 56 years old) first underwent several biopsies, followed in the end by a total laryngectomy. Diagnosis was histological. The patient developed regional and distant me...

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Detalles Bibliográficos
Autores principales: Mottola, Giampiero, Cascone, Anna Maria, Cavaliere, Matteo, Angrisani, Basilio, Fiorillo, Gabriella, Parente, Giuseppe, Volino, Fabrizio, Iemma, Maurizio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621131/
https://www.ncbi.nlm.nih.gov/pubmed/19046454
http://dx.doi.org/10.1186/1757-1626-1-365
Descripción
Sumario:BACKGROUND: We add a new rare illustrative case of osteosarcoma of the larynx to the literature. CASE PRESENTATION: The patient (man; 56 years old) first underwent several biopsies, followed in the end by a total laryngectomy. Diagnosis was histological. The patient developed regional and distant metastases and died of disease after 3 months from surgery. CONCLUSION: Osteosarcoma of the larynx is a rare and aggressive tumour with a poor long-term prognosis. The preferred treatment for this tumour is aggressive surgery. To perform a diagnosis we must be in presence of osteoid or of neoplastic osseous tissue directly produced by the neoplastic cells.