Cargando…
alpha-Actinin interacts with rapsyn in agrin-stimulated AChR clustering
AChR is concentrated at the postjunctional membrane at the neuromuscular junction. However, the underlying mechanism is unclear. We show that α-actinin, a protein known to cross-link F-actin, interacts with rapsyn, a scaffold protein essential for neuromuscular junction formation. α-Actinin, rapsyn,...
Autores principales: | Dobbins, G Clement, Luo, Shiwen, Yang, Zhihua, Xiong, Wen C, Mei, Lin |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621155/ https://www.ncbi.nlm.nih.gov/pubmed/19055765 http://dx.doi.org/10.1186/1756-6606-1-18 |
Ejemplares similares
-
Myasthenia gravis AChR antibodies inhibit function of rapsyn-clustered AChRs
por: Cetin, Hakan, et al.
Publicado: (2020) -
Agrin-induced reorganization of extracellular matrix components on cultured myotubes: relationship to AChR aggregation
Publicado: (1990) -
Clinical application of clustered-AChR for the detection of SNMG
por: Zhao, Guang, et al.
Publicado: (2015) -
A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome
por: Xing, Guanglin, et al.
Publicado: (2019) -
A Stable Cell Line Expressing Clustered AChR: A Novel Cell-Based Assay for Anti-AChR Antibody Detection in Myasthenia Gravis
por: Cai, Yu, et al.
Publicado: (2021)