Establishing an adjusted p-value threshold to control the family-wide type 1 error in genome wide association studies

BACKGROUND: By assaying hundreds of thousands of single nucleotide polymorphisms, genome wide association studies (GWAS) allow for a powerful, unbiased review of the entire genome to localize common genetic variants that influence health and disease. Although it is widely recognized that some correc...

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Detalles Bibliográficos
Autores principales: Duggal, Priya, Gillanders, Elizabeth M, Holmes, Taura N, Bailey-Wilson, Joan E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621212/
https://www.ncbi.nlm.nih.gov/pubmed/18976480
http://dx.doi.org/10.1186/1471-2164-9-516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621212/
https://www.ncbi.nlm.nih.gov/pubmed/18976480
http://dx.doi.org/10.1186/1471-2164-9-516

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