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Establishing an adjusted p-value threshold to control the family-wide type 1 error in genome wide association studies
BACKGROUND: By assaying hundreds of thousands of single nucleotide polymorphisms, genome wide association studies (GWAS) allow for a powerful, unbiased review of the entire genome to localize common genetic variants that influence health and disease. Although it is widely recognized that some correc...
Autores principales: | Duggal, Priya, Gillanders, Elizabeth M, Holmes, Taura N, Bailey-Wilson, Joan E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621212/ https://www.ncbi.nlm.nih.gov/pubmed/18976480 http://dx.doi.org/10.1186/1471-2164-9-516 |
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