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Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium
BACKGROUND: Follicular structures resembling germinal centres (GCs) that are characterized by follicular dendritic cell (FDC) networks have long been recognized in chronically inflamed tissues in autoimmune diseases, including the synovium of rheumatoid arthritis (RA). However, it is debated whether...
Autores principales: | Humby, Frances, Bombardieri, Michele, Manzo, Antonio, Kelly, Stephen, Blades, Mark C, Kirkham, Bruce, Spencer, Jo, Pitzalis, Costantino |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621263/ https://www.ncbi.nlm.nih.gov/pubmed/19143467 http://dx.doi.org/10.1371/journal.pmed.0060001 |
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