Cargando…

Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

BACKGROUND: Follicular structures resembling germinal centres (GCs) that are characterized by follicular dendritic cell (FDC) networks have long been recognized in chronically inflamed tissues in autoimmune diseases, including the synovium of rheumatoid arthritis (RA). However, it is debated whether...

Descripción completa

Detalles Bibliográficos
Autores principales: Humby, Frances, Bombardieri, Michele, Manzo, Antonio, Kelly, Stephen, Blades, Mark C, Kirkham, Bruce, Spencer, Jo, Pitzalis, Costantino
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621263/
https://www.ncbi.nlm.nih.gov/pubmed/19143467
http://dx.doi.org/10.1371/journal.pmed.0060001

Ejemplares similares