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Immunization with Single-Cycle SIV Significantly Reduces Viral Loads After an Intravenous Challenge with SIV(mac)239
Strains of simian immunodeficiency virus (SIV) that are limited to a single cycle of infection were evaluated for the ability to elicit protective immunity against wild-type SIV(mac)239 infection of rhesus macaques by two different vaccine regimens. Six animals were inoculated at 8-week intervals wi...
Autores principales: | Jia, Bin, Ng, Sharon K., DeGottardi, M. Quinn, Piatak, Michael, Yuste, Eloísa, Carville, Angela, Mansfield, Keith G., Li, Wenjun, Richardson, Barbra A., Lifson, Jeffrey D., Evans, David T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621341/ https://www.ncbi.nlm.nih.gov/pubmed/19165322 http://dx.doi.org/10.1371/journal.ppat.1000272 |
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