A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation

Chromosome structural changes with nonrecurrent endpoints associated with genomic disorders offer windows into the mechanism of origin of copy number variation (CNV). A recent report of nonrecurrent duplications associated with Pelizaeus-Merzbacher disease identified three distinctive characteristic...

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Detalles Bibliográficos
Autores principales: Hastings, P. J., Ira, Grzegorz, Lupski, James R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621351/
https://www.ncbi.nlm.nih.gov/pubmed/19180184
http://dx.doi.org/10.1371/journal.pgen.1000327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621351/
https://www.ncbi.nlm.nih.gov/pubmed/19180184
http://dx.doi.org/10.1371/journal.pgen.1000327

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