The IpaC Carboxyterminal Effector Domain Mediates Src-Dependent Actin Polymerization during Shigella Invasion of Epithelial Cells

Shigella, the causative agent of bacillary dysentery, invades epithelial cells by locally reorganizing the actin cytoskeleton. Shigella invasion requires actin polymerization dependent on the Src tyrosine kinase and a functional bacterial type III secretion (T3S) apparatus. Using dynamic as well as...

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Detalles Bibliográficos
Autores principales: Mounier, Joëlle, Popoff, Michel R., Enninga, Jost, Frame, Margaret C., Sansonetti, Philippe J., Van Nhieu, Guy Tran
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621354/
https://www.ncbi.nlm.nih.gov/pubmed/19165331
http://dx.doi.org/10.1371/journal.ppat.1000271

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