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Genetic Editing of HBV DNA by Monodomain Human APOBEC3 Cytidine Deaminases and the Recombinant Nature of APOBEC3G

Hepatitis B virus (HBV) DNA is vulnerable to editing by human cytidine deaminases of the APOBEC3 (A3A-H) family albeit to much lower levels than HIV cDNA. We have analyzed and compared HBV editing by all seven enzymes in a quail cell line that does not produce any endogenous DNA cytidine deaminase a...

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Detalles Bibliográficos
Autores principales:	Henry, Michel, Guétard, Denise, Suspène, Rodolphe, Rusniok, Christophe, Wain-Hobson, Simon, Vartanian, Jean-Pierre
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2625395/ https://www.ncbi.nlm.nih.gov/pubmed/19169351 http://dx.doi.org/10.1371/journal.pone.0004277

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