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Adjuvant 5-fluorouracil and folinic acid vs observation for pancreatic cancer: composite data from the ESPAC-1 and -3(v1) trials
The ESPAC-1, ESPAC-1 plus, and early ESPAC-3(v1) results (458 randomized patients; 364 deaths) were used to estimate the effectiveness of adjuvant 5FU/FA vs resection alone for pancreatic cancer using meta-analysis. The pooled hazard ratio of 0.70 (95% CI=0.55–0.88) P=0.003, and the median survival...
Autores principales: | Neoptolemos, J P, Stocken, D D, Tudur Smith, C, Bassi, C, Ghaneh, P, Owen, E, Moore, M, Padbury, R, Doi, R, Smith, D, Büchler, M W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2625958/ https://www.ncbi.nlm.nih.gov/pubmed/19127260 http://dx.doi.org/10.1038/sj.bjc.6604838 |
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